A systematic approach to the pathology of the digestive system
The Harvard Gastrointestinal, Liver, and Pancreatic Pathology 2026 course provides an extensive update on diagnostic surgical pathology, cytology and molecular testing involving the gastrointestinal tract, liver, gallbladder and pancreas.
The program emphasizes systematic interpretation of biopsy and resection specimens, standard gross and microscopic techniques, appropriate ancillary testing and practical diagnostic strategies that can be incorporated into daily clinical practice.
Core Diagnostic Areas
From biopsy pattern to final diagnosis
Biopsy
Specimen assessment
Morphology
Pattern recognition
Ancillary Tests
IHC & biomarkers
Molecular
Modern diagnostics
Diagnosis
Clinical integration
Three interconnected areas of modern pathology
The curriculum moves from upper and lower GI pathology into pancreaticobiliary disease and liver pathology, creating a broad but clinically focused digestive pathology update.
GI Pathology
Barrett’s esophagus, inflammatory disease, celiac disease, colitis, IBD, polyps, polyposis, colorectal cancer staging and GI lymphomas.
Pancreas & Biliary
Cytology, small biopsies, pancreatic tumors, gallbladder pathology, biliary tract disease and instructive pancreatic slide seminars.
Liver Pathology
Acute hepatitis, porto-sinusoidal vascular disease, autoimmune hepatitis, cholestatic disorders, hepatic tumors and HCC mimickers.
What you’ll be prepared to recognize and apply
The course is designed to translate contemporary pathology updates into practical diagnostic approaches for biopsy and resection specimens.
WHO Classification Updates
Discuss updates and newly described entities in digestive system tumor classification.
Inflammatory Disease
Recognize important differential diagnoses and morphological criteria for inflammatory GI disorders.
Biomarkers & Molecular Testing
Understand appropriate use of ancillary techniques and biomarkers in modern GI malignancies.
Liver Biopsy Interpretation
Integrate morphological patterns in liver biopsies with relevant clinical information.
Staging & Grading
Recognize appropriate application and limitations of disease staging and grading systems.
Pancreatic Diagnosis
Interpret pancreatic biopsy patterns and integrate pathology with clinical findings.
Move from theory to visual diagnosis
The program incorporates dedicated slide seminars and instructive cases to reinforce morphological interpretation across the upper GI tract, infectious GI disease and pancreatic pathology.
Inside the Harvard GI, Liver & Pancreatic Pathology program
A broad curriculum covering inflammatory disorders, precursor lesions, neoplasia, molecular diagnostics, cytology and organ-specific pathology.
Barrett’s Esophagus and Associated Neoplasia
Clinician’s Perspective — Upper GI Tract
Upper GI Tract Inflammatory Conditions
Gastric Polyps and Precursor Lesions
Celiac Disease and its Differential Diagnosis
Slide Seminar on Upper GI Tract
Biopsy Diagnosis of Colitis
IBD Controversies and Challenges
Colon Polyps and Polyposis
Challenges in Colon Cancer Staging
Endocrine Tumors of the Tubal Gut
Slide Seminar on Infectious Disorders of the GI Tract
GIST: From KIT to Succinate Dehydrogenase
Mesenchymal Tumors and Mesenchymal Polyps
GI Lymphomas
Molecular Diagnostics in GI Tract Malignancies
Anal Pathology Overview and Update
Appendiceal Tumors
Intraoperative Consultations in GI Pathology
Cytology and Small Biopsy Diagnosis of Pancreaticobiliary Tumors
Surgical Pathology of Pancreatic Tumors
Slide Seminar on Instructive Cases in Pancreatic Pathology
Gallbladder and Biliary Tract Pathology
Liver 1: Approach to Acute Hepatitis
Liver 2: Porto-Sinusoidal Vascular Disease
Clinician’s Perspective on Liver Biopsies
Autoimmune Hepatitis and Mimickers
Liver 3: Cholestatic Disorders
Hepatocellular Carcinoma and Mimickers
Morphology supported by modern pathology
Classification
Review updates and newly described entities in digestive system tumors.
Ancillary Techniques
Explore judicious application of immunohistochemistry in difficult diagnostic settings.
Molecular Pathology
Understand the growing role of molecular diagnostics in GI malignancies.
Biomarkers
Recognize biomarkers relevant to targeted therapies and clinical management.
Built for clinicians and pathology professionals
Pathologists
For academic, community and practicing pathologists seeking updates in GI, liver and pancreaticobiliary pathology.
Gastroenterologists
For specialists involved in the diagnosis and management of digestive system, pancreatic and liver disorders.
Trainees & Advanced Providers
Also relevant to specialty physicians, nurse practitioners, pathology assistants, laboratory staff and pathology trainees.
Everything organized for advanced study
Video Lectures
The complete educational lecture collection.
PDF Files
Supporting course documents for review and reference.
Subtitles
Subtitle resources included with the digital lectures.
Slide Seminars
Visual case-based learning integrated throughout the program.
A pathology course built around diagnostic decisions
The strength of this program is the combination of broad organ-system coverage with practical interpretation, slide seminars, molecular diagnostics and clinically relevant diagnostic strategies.
Broad Organ Coverage
GI tract, liver, gallbladder, biliary tract and pancreas are addressed within one integrated program.
Modern Diagnostics
Morphology is complemented by immunohistochemistry, molecular pathology and clinically significant biomarkers.
Practical Interpretation
The curriculum emphasizes biopsy interpretation, differential diagnosis, staging, grading and instructive cases.
Ready to explore the complete Harvard GI, Liver & Pancreatic Pathology program?
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